“I'm here to tell everyone that's this treatment works for me and my knee pain is a level 3 a little fluid is on my knee.”
PRP Therapy in St. Louis, MO
Platelet-rich plasma injections for knee, back, neck, and sciatica pain — STL Pain Center, South St. Louis County.
Knee pain that stops you from going up stairs. Back pain that has changed how you sleep. Joint damage that your doctor says needs surgery. These are the situations STL Pain Center’s Orthopedic Clinic was built for.
PRP therapy, or platelet-rich plasma therapy, is a regenerative approach that uses your body’s own healing factors to stimulate tissue repair and reduce inflammation at the exact site of damage. It is minimally invasive, uses no foreign substances, and has shown meaningful results for patients managing orthopedic conditions that have not responded to conservative treatment.
STL Pain Center offers PRP therapy as part of our Orthopedic Clinic services in South St. Louis County. Schedule your PRP evaluation at our Telegraph Road clinic, open Monday through Thursday.
What Is PRP Therapy?
Platelet-rich plasma therapy is a regenerative treatment that concentrates the platelets and growth factors naturally found in your blood, then injects this concentrated solution precisely at the site of injury or degeneration. Platelets are the cells your body already deploys to heal damaged tissue. PRP therapy amplifies that response.
The process begins with a simple blood draw. The blood is then processed through a centrifuge to separate and concentrate the platelet-rich plasma. This concentrated plasma, containing a much higher density of growth factors than your circulating blood, is injected into the joint or tissue under careful clinical guidance.
At the injection site, the concentrated growth factors stimulate collagen production, reduce inflammatory mediators, and signal surrounding tissue to begin repair processes. The result is not a pain blocker. It is a stimulus for actual healing, which means results develop over weeks as the tissue responds.
Most orthopedic clinics in the St. Louis area that offer PRP use standard centrifuge protocols. Ready to find out if PRP therapy is the right approach for your joint or tissue condition? Schedule a consultation at STL Pain Center.
Conditions We Treat with PRP Therapy in St. Louis
Knee Pain and Osteoarthritis
PRP therapy has some of its strongest evidence in knee osteoarthritis, where cartilage loss and chronic inflammation create the familiar grinding, stiffness, and pain cycle. The growth factors delivered by PRP can reduce inflammation and support the remaining cartilage in maintaining function. For patients not yet ready for knee replacement surgery, PRP represents a meaningful intermediate option that has allowed many to delay or avoid surgery entirely.
Back Pain from Joint Degeneration
Facet joint degeneration in the lumbar spine is a common cause of back pain in adults over 40 across South St. Louis County. When the small joints that connect vertebrae become arthritic and inflamed, the result is chronic low-grade pain that worsens with activity. PRP injected at facet joints can reduce the inflammatory cycle and support joint tissue health.
Sciatica from Joint and Disc Irritation
When sciatica involves inflammation around the sacroiliac joint or at disc-nerve interfaces, PRP’s anti-inflammatory mechanism can complement neuromodulation or neuropathy treatment to address both the structural and neurological dimensions of the condition.
Neck Pain and Cervical Joint Inflammation
Cervical facet joints and soft tissue injuries in the neck respond to PRP’s growth factor stimulation similarly to lumbar structures. For patients managing chronic neck pain from whiplash, degeneration, or cervical radiculopathy, PRP adds a regenerative dimension to their care.
Advantages of PRP Therapy at STL Pain Center
Uses Your Own Biology
PRP uses nothing foreign. Everything in the injection comes from your own blood. This eliminates allergic reaction risk and means the growth factors are recognized by your tissue as native healing agents.
Designed for Actual Repair, Not Symptom Masking
Cortisone injections reduce inflammation temporarily. PRP stimulates healing. The mechanism is fundamentally different, and for patients looking for outcomes beyond temporary relief, this distinction matters significantly.
Minimal Downtime
PRP therapy is performed in our clinic during a standard appointment. No hospital stay and no surgical recovery. Most patients can return to light activity shortly after their session.
Why Choose STL Pain Center for PRP Therapy?
PRP therapy is one of the core regenerative treatments offered through STL Pain Center’s Orthopedic Clinic. Dr. Andrew Morningstar and physical therapist Anissa Wheeler assess each patient’s specific joint condition and treatment history before recommending PRP, ensuring that patients who are the right candidates for this approach receive it with the precision it requires.
STL Pain Center’s Orthopedic Clinic brings PRP therapy together with hyaluronic acid injections and regenerative therapy to provide South County patients a complete non-surgical joint care program. Schedule your PRP evaluation today.
PRP Therapy Reviews
[TESTIMONIAL PLACEHOLDER — replace with real patient reviews that specifically mention PRP therapy before publishing]
Convenient Access from South St. Louis County
We proudly serve patients throughout St. Louis and the surrounding South County communities, including Oakville, Mehlville, St. Louis Hills, Fenton, Crestwood, Arnold, and South County.
Oakville: A short drive along Telegraph Road from the Oakville residential corridor.
Mehlville: Central to the Telegraph Road corridor that leads directly to our clinic.
Fenton and Arnold: Under 20 minutes via Telegraph Road southbound or I-55.
St. Louis Hills and Crestwood: Accessible via South Lindbergh Boulevard and Telegraph Road.
Located at 4455 Telegraph Rd #250, St. Louis, MO 63129. Many South County patients managing orthopedic conditions come to us after consultations at facilities in the Barnes-Jewish Hospital and Washington University Medical Center orbit. Our clinic brings non-surgical regenerative options closer to home in South St. Louis County. Ready to start? Contact STL Pain Center to schedule your PRP therapy evaluation.
Schedule Your PRP Therapy Evaluation
PRP therapy works best when the right patient receives it at the right stage of their condition. Schedule your evaluation at STL Pain Center’s Orthopedic Clinic and find out whether your joint damage is a good candidate for platelet-rich plasma treatment.
PRP therapy is one of three regenerative orthopedic treatments at STL Pain Center’s Orthopedic Clinic. Patients with knee osteoarthritis also benefit from hyaluronic acid injections for lubrication and cushioning. Those managing complex musculoskeletal degeneration may be candidates for our regenerative therapy program, which combines multiple modalities for a comprehensive approach.
PRP therapy is part of STL Pain Center’s complete Orthopedic Clinic program in South St. Louis County. Whether you are managing knee pain, back pain, or complex joint degeneration, our Orthopedic Clinic combines regenerative options to build the most effective non-surgical plan for your situation.
Real outcomes. Real people. Real St. Louis.
“Anissa Wheeler was my therapist. She is fantastic and very knowledgeable. She is very friendly and I would recommend STL Pain Center to everybody. I was having left knee pain and my doctor said that I needed knee surgery. I am 71 years old and I didn't want to go through surgery so I went to STL Pain Center to see if they could do me any good. I took a gel shot once a week for 5 weeks and they helped tremendously. If you are having knee pain I recommend STL Pain Center. Thank you very much Anissa Wheeler for all your help with relieving my knee pain.”
“Had a wonderful experience with this team! Everyone there is so caring and helped me through my knee treatments. Recommend them highly!”
Questions, answered.
Is PRP Therapy covered by insurance? +
How many sessions are typical? +
More from Orthopedic Clinic
Ready to talk about PRP Therapy?
Our team will walk you through the protocol, expected timeline, and how it fits your specific case.